She has appeared in the production Dance of the Dead, Eleventh Hour, and in an episode of CSI: Crime Scene Investigation titled World's End. Laura played a pregnant teenager in the episode of the fourth season of Private Practice called The Hardest Part which aired on March 31, 2011. She appeared in the 2011 film Hit List. In 2014 Laura appeared in the Law & Order: SVU episode, Comic Perversion as Carly Rydell.
In Summer 2010, Laura joined the Showtime dramedy Shameless, as Karen Jackson, a series regular. After a successful first season, the show was renewed for a second season, which premiered January 8, 2012. Laura remained part of the main cast as a series regular for the first two seasons. For season three, she became a recurring series member.